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Once-weekly tirzepatide versus once-daily insulin degludec as add-on to metformin with or without SGLT2 inhibitors in patients with type 2 diabetes (SURPASS-3): a randomised, open-label, parallel-group, phase 3 trial

Clinicians advise caution until controlled trials confirm benefits and safety

The same compound delivered topically through a serum, applied with microneedling, injected directly into the scalp, or injected subcutaneously into the abdomen will produce very different biological effects

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